No!
Windows 8 Consumer Preview includes Windows Defender, which has actually been boosted in Windows 8 to supply the same degree of malware protection as Microsoft Security Essentials.
You do not should put up Microsoft Security Essentials and it will certainly not work with Windows 8. Microsoft will continue to provide and enhance Microsoft Security Essentials for Windows 7, Windows Vista, and Windows XP. If you are upgrading to Windows 8 Consumer Preview, you need to uninstall Microsoft Security Essentials.
For information on uninstalling Microsoft Security Essentials, see the following Knowledge Base article:http://support.microsoft.com/kb/2483120.
